I'll spare you the lame effort I was writing on the same subject and instead link to what Joss wrote over at Whedonesque.
"What is wrong with women?
I mean wrong. Physically. Spiritually. Something unnatural, something destructive, something that needs to be corrected.
How did more than half the people in the world come out incorrectly? I have spent a good part of my life trying to do that math, and I’m no closer to a viable equation. And I have yet to find a culture that doesn’t buy into it. Women’s inferiority – in fact, their malevolence -- is as ingrained in American popular culture as it is anywhere they’re sporting burkhas. I find it in movies, I hear it in the jokes of colleagues, I see it plastered on billboards, and not just the ones for horror movies. Women are weak. Women are manipulative. Women are somehow morally unfinished. And the logical extension of this line of thinking is that women are, at the very least, expendable."